Craving comfort food that combines two all-time favorites—mac and cheese and meatloaf? Look no further! This Mac and Cheese Meatloaf Casserole is the ultimate dish to satisfy your comfort cravings. Packed with cheesy goodness, savory meat, and a variety of seasonings, this casserole is a surefire hit for family dinners, potlucks, or when you simply want to indulge. Let’s dive into the recipe and explore how to make this dish irresistible!

What is Mac and Cheese Meatloaf Casserole?
Mac and Cheese Meatloaf Casserole is a delightful fusion of two classic American dishes: creamy, cheesy mac and cheese paired with a savory, seasoned meatloaf. The dish layers cooked macaroni with a rich cheese sauce on top of a flavorful meatloaf base, creating a casserole that’s hearty, filling, and oh-so-satisfying. It’s the perfect solution for when you can’t decide between mac and cheese or meatloaf for dinner—why not have both?
Ingredients List for Mac and Cheese Meatloaf Casserole
For the Meatloaf Layer:
- 1 ½ lbs ground beef (You can also use a mix of ground beef and pork)
- 1 cup breadcrumbs (plain or seasoned)
- 1 large egg
- 1 small onion, finely diced
- 2 cloves garlic, minced
- ¼ cup ketchup (plus extra for topping)
- 1 tablespoon Worcestershire sauce
- 1 tablespoon Dijon mustard
- 1 teaspoon salt
- ½ teaspoon black pepper
- 1 teaspoon Italian seasoning (optional)
For the Mac and Cheese Layer:
- 2 cups elbow macaroni, uncooked
- 2 cups shredded sharp cheddar cheese
- 1 cup shredded mozzarella cheese (optional for extra creaminess)
- 2 tablespoons butter
- 2 tablespoons all-purpose flour
- 2 cups milk (whole or 2%)
- ½ teaspoon salt
- ¼ teaspoon black pepper
- ¼ teaspoon paprika (optional)
- ¼ cup grated Parmesan cheese (optional, for topping)
Substitutions and Variations
This Mac and Cheese Meatloaf Casserole recipe is versatile, and you can easily make substitutions to suit your preferences or dietary needs. Here are a few ideas:
- Ground Turkey or Chicken: If you prefer a lighter version, swap the ground beef with ground turkey or chicken.
- Gluten-Free Option: Use gluten-free breadcrumbs in the meatloaf and gluten-free pasta for the mac and cheese. You can also replace all-purpose flour with a gluten-free flour blend for the cheese sauce.
- Vegetarian Version: Skip the meatloaf entirely and instead layer roasted vegetables, like zucchini, eggplant, and mushrooms, under the mac and cheese for a veggie-friendly twist.
- Cheese Variety: Don’t limit yourself to cheddar—feel free to experiment with other types of cheese like Gouda, Monterey Jack, or even a sharp blue cheese for extra flavor.
- Add Veggies: Sneak in extra nutrients by adding vegetables like peas, spinach, or chopped bell peppers to the mac and cheese.
Step-by-Step Cooking Instructions

Cooking this casserole is as simple as following these easy steps. The meatloaf and mac and cheese come together perfectly for a delightful casserole that will impress everyone.
How to Cook Mac and Cheese Meatloaf Casserole: A Step-by-Step Guide
Step 1: Preheat the Oven
Preheat your oven to 350°F (175°C). Grease a 9x13-inch casserole dish or baking pan to prevent sticking.
Step 2: Prepare the Meatloaf Base
- In a large bowl, combine the ground beef (or your choice of meat), breadcrumbs, egg, diced onion, garlic, ketchup, Worcestershire sauce, Dijon mustard, salt, pepper, and Italian seasoning.
- Mix everything together until just combined—be careful not to overmix, as that can make the meatloaf tough.
- Press the meat mixture evenly into the bottom of your greased casserole dish, forming a smooth, even layer.
- If desired, spread a thin layer of ketchup on top of the meatloaf for extra flavor and a nice glaze.
Step 3: Cook the Macaroni
- While the meatloaf bakes, cook the elbow macaroni according to the package instructions. Make sure to cook it al dente (about 6–7 minutes) so it doesn’t get mushy when baked.
- Drain and set aside.
Step 4: Make the Cheese Sauce
- In a medium saucepan, melt the butter over medium heat. Once melted, whisk in the flour and cook for about 1–2 minutes to create a roux.
- Gradually add the milk, whisking constantly to avoid lumps. Continue whisking until the mixture thickens, about 5 minutes.
- Stir in the shredded cheddar and mozzarella cheeses, salt, pepper, and paprika. Continue stirring until the cheese is fully melted and the sauce is smooth.
Step 5: Assemble the Casserole
- Once the meatloaf has baked for about 20 minutes and is partially cooked, remove it from the oven.
- Pour the cooked and drained macaroni over the meatloaf layer.
- Top the macaroni with the cheese sauce, making sure to cover all the pasta evenly.
- For an extra cheesy finish, sprinkle the Parmesan cheese over the top.
Step 6: Bake the Casserole
Place the assembled casserole back in the oven and bake for another 20–25 minutes, or until the top is golden and bubbly. The meatloaf should be fully cooked, and the cheese sauce should be bubbling around the edges.
Step 7: Let It Rest
Once the casserole is done baking, let it rest for 5–10 minutes before serving. This helps the layers set and makes it easier to cut into slices.
Common Mistakes to Avoid
- Overmixing the Meatloaf: Overworking the meat mixture can lead to a tough, dense meatloaf. Mix just until the ingredients are combined.
- Overcooking the Pasta: Be sure to cook your macaroni al dente. Overcooked pasta will become too soft and soggy after baking.
- Not Seasoning Enough: Both the meatloaf and cheese sauce need good seasoning. Taste the cheese sauce before pouring it over the pasta to make sure it’s flavorful enough.
Serving and Presentation Tips
Now that your Mac and Cheese Meatloaf Casserole is ready, it’s time to serve it up! Here are some tips to make it even more appealing.
How to Serve Mac and Cheese Meatloaf Casserole
- Slice Like a Lasagna: Use a sharp knife to cut clean slices through the layers. Serve the slices on a plate, ensuring each piece gets a good portion of both meatloaf and cheesy macaroni.
- Add a Side Salad: A fresh green salad with a tangy vinaigrette is the perfect complement to the rich and hearty casserole.
- Crusty Bread: Serve with a side of warm, crusty bread to soak up any extra cheese sauce.
Presentation Ideas for Mac and Cheese Meatloaf Casserole
- Cheese Pull: When serving, gently pull a slice away from the rest of the casserole to showcase that irresistible cheese pull for a perfect Instagram moment.
- Garnish with Fresh Herbs: For added color and freshness, sprinkle some chopped parsley or chives on top of the casserole before serving.
Mac and Cheese Meatloaf Casserole Recipe Tips
- Use High-Quality Cheese: The quality of your cheese can make or break this dish. Opt for good quality cheddar and mozzarella for the creamiest, richest flavor.
- Make Ahead: This casserole can be made ahead of time and refrigerated. When you’re ready to bake, just pop it in the oven and add an extra 10–15 minutes to the cooking time.
- Freeze for Later: You can freeze this casserole before baking. Wrap it tightly in plastic wrap and foil, and freeze for up to 3 months. When ready to eat, thaw overnight in the refrigerator and bake as instructed.
Frequently Asked Questions (FAQs)
Q: Can I use other types of pasta for this casserole?
A: Absolutely! While elbow macaroni is traditional, you can use any small pasta shape, such as rotini, shells, or penne.
Q: Can I make this casserole ahead of time?
A: Yes, you can prepare the entire casserole, refrigerate it, and bake it the next day. Just add some extra time to ensure it heats through.
Q: What should I do if the top gets too brown before the casserole is done?
A: If the cheese topping starts to brown too quickly, simply cover the casserole with aluminum foil and continue baking until it’s fully cooked.
Q: How do I know when the meatloaf layer is cooked through?
A: Use a meat thermometer to check the internal temperature of the meatloaf. It should reach 160°F (70°C) when fully cooked.
Conclusion
The Mac and Cheese Meatloaf Casserole is a must-try recipe that merges the comforting flavors of creamy mac and cheese with the hearty goodness of classic meatloaf. Whether you’re cooking for a crowd or simply treating yourself, this dish is sure to satisfy. With a few simple ingredients and step-by-step instructions, you’ll be able to serve up a delicious, cheesy, and savory meal that’s sure to become a household favorite. Don’t wait—try this recipe today and enjoy the best of both worlds in one delightful casserole!
PrintMac And Cheese Meatloaf Casserole Recipe
This Mac and Cheese Meatloaf Casserole combines classic comfort foods—savory meatloaf and creamy mac and cheese—into one delicious dish. Made with ground beef, elbow macaroni, cheddar cheese, and a rich meat sauce, it's an ideal recipe for family dinners. Enjoy layers of cheesy goodness with hearty meat flavors, perfect for a cozy meal. Serve it as a quick weeknight dinner or bring it to your next potluck.
- Prep Time: 15 minutes
- Cook Time: 35-40 minutes
- Total Time: 50-55 minutes
- Yield: 6 servings 1x
- Category: Main Course
- Method: Baking
- Cuisine: American
- Diet: Gluten Free
Ingredients
- 1 lb ground beef
- 1 cup breadcrumbs
- 1 egg
- 2 cups cooked elbow macaroni
- 2 cups shredded cheddar cheese
- ½ cup milk
- 1 small onion, chopped
- 2 cloves garlic, minced
- Salt and pepper, to taste
- 1 tbsp ketchup
- 1 tbsp Worcestershire sauce
Instructions
- Preheat the oven to 350°F (175°C).
- In a bowl, combine ground beef, breadcrumbs, egg, onion, garlic, ketchup, Worcestershire sauce, salt, and pepper.
- Press the meat mixture into the bottom of a greased casserole dish to form an even layer.
- Bake the meatloaf layer for 20 minutes.
- In a separate bowl, mix the cooked macaroni, shredded cheddar cheese, and milk.
- Spread the mac and cheese mixture evenly on top of the baked meatloaf.
- Bake for an additional 15-20 minutes until the cheese is melted and bubbly.
- Let cool for a few minutes before serving.
Notes
- You can substitute ground turkey or chicken for the beef.
- Add a layer of barbecue sauce on top of the meatloaf for extra flavor.
- Garnish with fresh parsley or chives before serving for a pop of color.
Nutrition
- Serving Size: 1 slice (approx. ⅙th of the casserole)
- Calories: 450 kcal
- Sugar: 3g
- Sodium: 650mg
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