There's nothing quite like a hearty, comforting meatloaf fresh from the oven, but when you add gooey, melty mozzarella in the middle, it becomes truly unforgettable. This Mozzarella Stuffed Meatloaf takes a classic dinner favorite to the next level with its cheesy surprise inside.

I first made this recipe on a chilly Sunday afternoon, looking for a way to make traditional meatloaf a bit more exciting for my family. Now, it’s one of our most requested meals, perfect for both weeknights and special occasions. Let’s dive into what makes this recipe so incredible.

Why You'll Love This Mozzarella Stuffed Meatloaf

Get ready to fall in love with your new go-to meatloaf recipe. Not only does it deliver on flavor, but it also has a show-stopping presentation that will impress even the pickiest eaters.

First, this recipe is incredibly easy to prepare. Even if you’re a beginner in the kitchen, you’ll be able to follow the steps and achieve perfect results.

Second, the combination of savory ground beef, aromatic seasonings, and creamy mozzarella is simply irresistible. Every slice reveals a delicious cheesy core that oozes with every bite.

Finally, it’s a budget-friendly meal that uses pantry staples and affordable ingredients. You can feed the whole family without breaking the bank, and leftovers (if there are any!) taste just as good the next day.

If you’re looking for a dish that combines comfort, flavor, and a touch of elegance, this Mozzarella Stuffed Meatloaf is the one for you.

Ingredients Notes

The beauty of this meatloaf is in its simple yet flavorful ingredients. Each one plays a role in creating a juicy, tender loaf with a cheesy surprise inside.

Ground beef is the star of the show. Use an 80/20 mix for the perfect balance of flavor and moisture. Too lean, and your meatloaf may turn out dry.

Breadcrumbs bind the mixture together, giving the meatloaf its structure. Plain or Italian-seasoned breadcrumbs both work well, but the latter adds an extra burst of flavor.

Eggs are the glue that holds the ingredients together. They also add a touch of richness to the meat mixture.

The mozzarella cheese is the hero of the recipe. Opt for low-moisture mozzarella to prevent the cheese from becoming too watery during baking. A whole mozzarella log or pre-cut sticks are ideal for the stuffing.

A blend of ketchup and Worcestershire sauce in the glaze gives the perfect balance of sweetness and tang. Feel free to adjust the glaze to your taste, adding a pinch of chili powder for a hint of spice if desired.

Special equipment: A loaf pan helps maintain the shape, but you can also mold the meatloaf by hand on a baking sheet for a more rustic look.

How To Make This Mozzarella Stuffed Meatloaf

Creating this delicious meatloaf is simpler than you might think. Follow these steps to achieve a perfectly juicy, cheesy masterpiece.

Start by preheating your oven to 375°F (190°C) and lining a baking sheet with parchment paper or foil for easy cleanup.

In a large mixing bowl, combine the ground beef, breadcrumbs, eggs, minced garlic, diced onion, Worcestershire sauce, and seasonings. Use your hands to mix everything gently but thoroughly, ensuring the ingredients are evenly distributed.

Lay out a large piece of parchment paper or wax paper and spread the meat mixture into a rectangle about 1 inch thick. Place the mozzarella in the center of the rectangle, leaving some space on all sides. Carefully roll the meat mixture around the cheese, sealing the edges to create a loaf shape.

Transfer the meatloaf to your prepared baking sheet. Brush the top with a generous layer of ketchup glaze for a shiny, flavorful finish.

Bake for 45-50 minutes, or until the internal temperature reaches 160°F (71°C). Let the meatloaf rest for 5-10 minutes before slicing to allow the juices to redistribute and the cheese to set slightly.

From start to finish, you’re looking at about an hour, making this recipe ideal for a weeknight dinner or a weekend treat.

Storage Options

If you happen to have leftovers, this meatloaf stores beautifully and makes for an even tastier second meal.

For refrigeration, store slices in an airtight container for up to 3 days. To keep it moist, add a spoonful of the glaze or a drizzle of broth before reheating.

If you prefer freezing, wrap individual slices tightly in plastic wrap and store them in a freezer-safe bag for up to 3 months. Thaw overnight in the fridge before reheating.

To reheat, warm slices in a 350°F oven for 10-15 minutes, or microwave on a low setting in 30-second intervals until heated through.

Variations and Substitutions

This Mozzarella Stuffed Meatloaf is endlessly adaptable, making it easy to customize based on your preferences and dietary needs.

For a leaner option, swap the ground beef with ground turkey or chicken. You may need to add an extra egg or a splash of milk to maintain moisture.

Experiment with different cheeses like provolone, cheddar, or pepper jack for a unique flavor twist.

Add a layer of sautéed spinach, roasted red peppers, or caramelized onions between the meat and cheese for added depth of flavor and a veggie boost.

Want to spice it up? Mix some crushed red pepper flakes or diced jalapeños into the meat mixture for a touch of heat.

Lastly, try a barbecue glaze instead of ketchup for a smoky-sweet twist on the classic.

No matter how you make it, this Mozzarella Stuffed Meatloaf is guaranteed to bring smiles to the dinner table. Don’t be afraid to experiment and make it your own!